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Head and Neck Cancer

Recent studies from University of Colorado add new data to head and neck cancer

Published in Cancer Weekly, January 29th, 2008

According to recent research from the United States, "Purpose To establish the safety and toxicity profile of daily gefitinib with radiation alone or with concurrent chemoradiotherapy in previously untreated patients with locally advanced squamous cell head and neck cancer (LAHNC). Patients and Methods Patients with intermediate-stage LAHNC were treated with concomitant boost radiation (RT) alone with escalating doses of daily gefitinib (250 or 500 mg; cohort I)."

"Once a safety profile was determined with RT alone, patients with high-risk disease were then treated with daily gefitinib (250 or 500 mg), weekly cisplatin (CDDP; 30 mg/m(2)), and once-daily RT (cohort II)....

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