Alloimmunization

New alloimmunization findings from M.H. Yazer and co-researchers published

Published in Cancer Weekly, January 29th, 2008

"The D antigen is highly immunogenic, requiring only a small quantity of transfused red blood cells (RBCs) to cause alloimmunization in D- immunocompetent recipients. The relatively low sensitization rate in oncology patients transfused with D+ platelets is well documented," scientists in the United States report.

"A study of the alloimmunization rate of primarily nononcology D- recipients transfused with D+ RBCs was undertaken. Transfusion service records were examined to identify D- recipients who were not alloimmunized to the D antigen and who had a follow-up antibody screen performed at least 10 days after the initial D+ RBC transfusion(s). The age and sex of the...

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Source: Cancer Weekly (2008-01-29)

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