Cancer Vaccines
Reports from P. Nanni and co-researchers add new data to research in cancer vaccines
Published in Cancer Weekly, January 29th, 2008
"The development of prophylactic cancer vaccines that protect healthy hosts from tumor development leaves open the question whether such vaccines are also effective against established tumors and metastases. We tested the therapeutic activity of a proven prophylactic anti-HER-2/neu vaccine against successive stages of mammary carcinoma progression in HER-2/neu transgenic mice," scientists writing in the journal Cancer Research report.
"The vaccine consisted of transgenic mammary carcinoma cells expressing HER-2/neu and two adjuvants: allogeneic class I histocompatibility antigens and interleukin (IL)-12. Vaccination of mice bearing lung micrometastases resulted...
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Source: Cancer Weekly (2008-01-29)
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