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Cancer Vaccines

Research on cancer vaccines detailed by scientists at University of Virginia

Published in Cancer Weekly, February 5th, 2008

Data detailed in 'The TAG family of cancer/testis antigens is widely expressed in a variety of malignancies and gives rise to HLA-A2-restricted epitopes' have been presented. "The TAG-1, TAG-2a, TAG-2b, and TAG-2c cancer/testis genes, known to be expressed in an unusually high percentage of melanoma cell lines, are shown here to be expressed in a variety of tumor lines of diverse histologic type, including cancers of the brain, breast, colon, lung, ovary, pharynx, and tongue. The genes are also expressed in fresh, uncultured melanoma, and ovarian cancer cells," scientists in the United States report.

"Epitope prediction algorithms were used to identify potential HLA-A1,...

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