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Nasopharyngeal Carcinoma

Studies from G. Zhou et al further understanding of nasopharyngeal carcinoma

Published in Cancer Weekly, February 5th, 2008

"Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of AMP genes, which can affect the respective MMP production in an allele,specific manner, have been well characterized," scientists in Beijing, People's Republic of China report.

"We examined whether these functional polymorphisms were related to the risk of nasopharyingeal carcinoma (NPC) in Chinese populations. Eight polymorphisms in the promoter of MMPI, MMP2, MMP3, MMP7, MMP9, MMP12, and MMP13 were genotyped in two independent case-control populations; one is from Guangxi province (593 patients with NPC and 480 controls),...

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