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Ovarian Cancer

Studies from M.L. Puiffe and co-researchers in the area of ovarian cancer published

Published in Cancer Weekly, February 5th, 2008

"At least one third of all cases of epithelial ovarian cancer are associated with the production of ascites, although its effect on tumor cell microenvironment remains poorly understood. This study addresses the effect of the heterologous acellular fraction of ovarian cancer - derived ascites on a cell line (OV-90) derived from the chemotherapy- nai ve ovarian cancer patient," scientists writing in the journal Neoplasia report.

"Ascites were assayed for their effect on cell invasion, growth, and spheroid formation. When compared to either no serum or 5% serum, ascites fell into one of two categories: stimulatory or inhibitory. RNA from OV- 90 cells exposed to...

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