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Angiogenesis

Reports outline angiogenesis research from Cleveland Clinic

Published in Cancer Weekly, February 5th, 2008

New research, 'Angiogenesis in melanoma,' is the subject of a report. According to a study from the United States, "The process of angiogenesis is crucial for progression and metastasis of the majority of solid tumors including melanomas. The current review summarizes existing knowledge of the mechanisms of angiogenesis in melanoma, as well as current anti-angiogenic therapeutic strategies and their targets."

"We focus primarily on the role of key growth factors that are secreted by melanoma cells and known to trigger angiogenic responses, and their receptors as expressed on both endothelial and melanoma cells. Many of these growth factors function in synergy with...

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