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Cord Blood

Research reports on cord blood from M.D. Anderson Cancer Center provide new insights

Published in Cancer Weekly, February 5th, 2008

Fresh data on cord blood are presented in the report 'Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing.' According to a study from the United States, "Advances in immune assessment, including the development of T-cell receptor excision circle (TREC) assays of thymopoiesis, cytokine-flow cytometry assays of T-cell function, and higher-order phenotyping of T-cell maturation subsets have improved our understanding of T-cell homeostasis. Limited data exist using these methods to characterize immune recovery in adult cord blood (CB) transplant recipients, in whom infection is a leading cause of...

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