Fanconi Anemia Genetics
Researchers from Rabin Medical Center, Department of Medical Genetics report on findings in fanconi anemia genetics
Published in Cancer Weekly, February 5th, 2008
Investigators publish new data in the report 'Prevalence of breast and colorectal cancer in Ashkenazi Jewish carriers of Fanconi anemia and Bloom syndrome.' "Fanconi anemia complementation group C and Bloom syndrome, rare autosomal recessive disorders marked by chromosome instability, are especially prevalent in the Ashkenazi* Jewish community. A single predominant mutation for each has been reported in Ahshkenazi Jews: c.711+4A-- >T (IVS4 +4 A-- >T) in FACC and BLM(Ash) in Bloom syndrome," scientists in Petah Tikva, Israel report.
"Individuals affected by either of these syndromes are characterized by susceptibility for developing malignancies, and we questioned...
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Source: Cancer Weekly (2008-02-05)
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