Life Sciences
New life sciences study findings have been reported by scientists at Tel-Aviv University, George S. Wise Faculty of Life Sciences
Published in Cancer Weekly, February 5th, 2008
Data detailed in 'Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications' have been presented. According to recent research published in the Journal of Biological Chemistry, "Eukaryotic Na(+)/H(+) exchangers are transmembrane proteins that are vital for cellular homeostasis and play key roles in pathological conditions such as cancer and heart diseases. Using the crystal structure of the Na(+)/H(+) antiporter from Escherichia coli (EcNhaA) as a template, we predicted the three-dimensional structure of human Na(+)/H(+) exchanger 1 (NHE1)."
"Modeling was particularly challenging because of the extremely low sequence identity...
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Source: Cancer Weekly (2008-02-05)
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