Life Sciences
Research from National Institutes of Health reveals new findings on life sciences
Published in Cancer Weekly, February 5th, 2008
Scientists discuss in 'cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines' new findings in life sciences. According to a study from the United States, "The phosphorylation of histone H3 is known to play a role in regulation of transcription as well as preparation of chromosomes for mitosis. Various signaling cascades induce H3 phosphorylation, particularly at genes activated by these pathways."
"In this study, we show that signaling can also have the opposite effect. Activators of cAMP signaling induce a rapid and potent loss of H3 phosphorylation. This effect is not mediated through a cAMP metabolite since a...
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Source: Cancer Weekly (2008-02-05)
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