Cervical Cancer

Researchers from Washington University, Medical Department provide details of new studies and findings in the area of cervical cancer

Published in Cancer Weekly, February 12th, 2008

According to a study from the United States, "We previously mapped a nonrandom frequent loss of heterozygosity (LOH) region in cervical cancers to 1 Mb of 6p23. Here, we describe the identification of a novel cervical cancer susceptibility gene, CD83."

"The gene was identified by several complementary approaches, including a family-based association study, comparison of transcript expression in normal and cancerous tissue, and genomic sequencing of candidate. CD83 encodes an inducible glycoprotein in the immunoglobulin superfamily and is a marker for mature dendritic cells. The association study that includes 377 family trios showed that five single nucleotide...

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Source: Cancer Weekly (2008-02-12)

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