Hematologic Disease

Study findings on hematologic disease are outlined in reports from D. Caillot and colleagues

Published in Cancer Weekly, February 12th, 2008

"invasive aspergillosis (IA) has a poor prognosis in immunocompromised patients. Combinations of drugs that act on different targets are expected to improve the clinical efficacy of separate compounds," scientists in Dijon, France report.

"Patients with proven or probable IA were randomized in a prospective, open pilot study to receive either a combination of liposomal amphotericin B (AmB) at the standard dose (3 mg/kg daily) and caspofungin at the standard dose or monotherapy with a high-dose AmB regimen (10 mg/kg daily). Thirty patients (21 men and 9 women) with hematologic malignancies were analyzed, and there were 15 patients in each arm. The median duration of...

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Source: Cancer Weekly (2008-02-12)

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