Published in Cancer Weekly, February 12th, 2008
"Two separate dose-escalating arms (arm A and arm B) were conducted simultaneously. Patients received pemetrexed on day 1 (D1) (500-600 mg/m(2) IV) every 21 days. In arm A, bortezomib was given twice weekly (0.7-1.3 mg/m(2) on D1, 4, 8, and 11). In arm B, bortezomib was given weekly (1.0-1.6 mg/m(2) on D1 and 8). We treated 27 patients on four dose levels in arm A...
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Source: Cancer Weekly (2008-02-12)
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