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Breast Cancer

Data from M. Kaufmann et al provide new insights into breast cancer

Published in Cancer Weekly, February 12th, 2008

According to a study from Frankfurt, Germany, "GABG-IV B-93 is a prospective, randomised study comparing goserelin (n=384) with no further treatment (n=392) in hormone receptor (HR)-negative breast cancer patients (n=465) after 3 cycles cyclophosphamide, methotrexate, 5-fluorouracil (CMF) for patients with 0 - 3 positive lymph nodes (LN) or 4 cycles epirubicin, cyclophosphamide (EC) followed by 3 cycles CMF for patients with 4 - 9 positive LN. After completion of the ZEBRA trial the study was amended to enrol also HR-positive patients with 1 - 9 + LN (n=311)."

"After a median follow-up of 4.7 years neither HR-negative nor HR-positive patients showed a benefit for...

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