Breast Cancer
Researchers at University of Texas target breast cancer
Published in Cancer Weekly, February 12th, 2008
According to recent research published in the journal Cancer Research, "CCAAT/enhancer binding protein (C/EBP) is a transcription factor implicated in the control of development, differentiation, and proliferation of mammary epithelial cells' However, it remains unclear how C/EBP is involved in tumor suppression through its interaction with specific downstream genes in breast cancer. Tumor cells overexpress serine proteases, which play crucial roles in tumor invasion and metastasis."
"Elafin is an endogenous serine protease inhibitor and is transcriptionally down-regulated in most tumor cell lines. In this study, we show that C/EBP beta is differentially...
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Source: Cancer Weekly (2008-02-12)
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