Breast Cancer
Scientists at University of London, Imperial College target breast cancer
Published in Cancer Weekly, February 12th, 2008
"Lipid rafts are membrane platforms that spatially organize molecules for specific signaling pathways that regulate various cellular functions. Cholesterol is critical for liquid-ordered raft formation by serving as a spacer between the hydrocarbon chains of sphingolipids, and alterations in the cholesterol contents of the plasma membrane causes disruption of rafts," researchers in Kensington, the United Kingdom report.
"The role that sigma receptors play in cancer is not clear, although it is frequently up-regulated in human cancer cells and tissues and a receptors inhibit proliferation in carcinoma and melanoma cell lines, induce apoptosis in colon and mammary...
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Source: Cancer Weekly (2008-02-12)
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