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Plexxikon Announces Publication of Key Data Demonstrating Possible Personalized Medicine for a Variety of Cancers

Published in Cancer Weekly, March 4th, 2008

Plexxikon Inc. announced the publication of data from studies of Plexxikon's targeted cancer compound published in The Proceedings of the National Academy of Sciences by a team of scientists from Plexxikon and the Wistar Institute. Plexxikon's novel anti-cancer compound selectively destroys tumor cells which contain the B-Raf(V600E) cancer-causing mutation, a defect present in most melanomas and thyroid tumors and a large number of colorectal and other cancers. Patients with the BRAF(V600E) gene may have particularly aggressive tumors often resulting in much poorer survival outcomes.

Using its proprietary Scaffold-Based Drug Discovery(TM) platform, Plexxikon has...

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