Myelofibrosis
Research results from Odense University update knowledge of myelofibrosis
Published in Cancer Weekly, March 11th, 2008
According to recent research from Odense, Denmark, "A retrospective study of 38 essential thrombocythemia (ET) patients was conducted, reviewing bone marrow biopsies according to WHO criteria using a semiquantitative scoring system. Four patients did not fulfil the WHO criteria for a myeloproliferative disorder and one biopsy was insufficient for evaluation. 14 patients were reclassified as having prefibrotic idiopathic myelofibrosis (IMF), whilst the ET diagnosis was sustained in 19 patients."
"The individual bone marrow parameters of the reviewed diagnosis showed no correlation with JAK2 V617F mutation status, which was determined by a highly sensitive quantitative...
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Source: Cancer Weekly (2008-03-11)
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