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Cancer Gene Therapy
Researchers from University of Arizona discuss findings in cancer gene therapy
March 11th, 2008
New investigation results, 'Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells,' are detailed in a study published in Molecular Cancer Therapeutics. "The PRL phosphatases have been implicated in cancer cell growth and metastasis in a variety of tumor types. Using cDNA microarray, we previously identified and reported PRL-1 as being highly up-regulated in pancreatic cancer cell lines," investigators in the United States report. "In this study, we sought to further evaluate the expression of all three PRL phosphatases in pancreatic cancer cell lines and extend our...
Source: Cancer Weekly (2008-03-11)
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