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Cancer Weekly

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Cancer Gene Therapy



University of Leeds, Leeds Institute of Molecular Medicine describes research in cancer gene therapy



March 11th, 2008

A report, 'Carcinoembryonic antigen cell adhesion molecule 6 predicts breast cancer recurrence following adjuvant tamoxifen,' is newly published data in Clinical Cancer Research. According to recent research from Leeds, the United Kingdom, "Tamoxifen remains therapy of choice for premenopausal estrogen receptor alpha-positive breast cancer. However, resistance and recurrence are serious problems."

"Our previous work indicated that carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) was significantly up-regulated in tamoxifen-resistant (TAMr) MCF-7 derivatives. The aim of this study was to determine the functional role of CEACAM6 in endocrine-resistant...


Source: Cancer Weekly (2008-03-11)

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