Cancer Weekly
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Fusion Proteins
New fusion proteins study findings have been reported by U. Petrausch and colleagues
March 11th, 2008
New research, 'A33scFv-green fluorescent protein, a recombinant single-chain fusion protein for tumor targeting,' is the subject of a report. According to recent research from Berlin, Germany, "Chemical conjugates of monoclonal antibodies with fluorophores or enzymes have long been used for diagnostic purposes and experimental therapeutic approaches. Recombinant technology allows for the design and expression of tailored genuine fusion proteins, providing defined molecules as to size, molar ratios of the functional components and stability." "The production of functional protein, however, is often limited or impossible due to refolding and solubility problems. Here, we...
Source: Cancer Weekly (2008-03-11)
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