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Cancer Weekly

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Acute Lymphoblastic Leukemia



New acute lymphoblastic leukemia study findings have been reported by S. Struski and colleagues



March 11th, 2008

According to a study from Strasbourg, France, "Association of a t(9;22)(q34;q11), BCR/ABL-positive, with a dic(19;21)(p13;p13) has been described in acute lymphoblastic leukemia in relapse, raising the question of whether this association is recurrent."

"Described here are two cases, one of myeloproliferative disease and one of acute lymphoblastic leukemia, both presenting a masked t(9;22) and t(19;21). Chromosomal rearrangements were ascertained by fluorescence in situ hybridization (FISH) using locus-specific probes, multi-color FISH, and bacterial artificial chromosome array," wrote S. Struski and colleagues.

The researchers concluded: "These...


Source: Cancer Weekly (2008-03-11)

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