Cancer Weekly
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Basal Cell Cancer
Researchers' work from Indiana University, Medical Department focuses on basal cell cancer
March 11th, 2008
According to a study from the United States, "The OCT4 transcription factor is a marker of pluripotency and is present in embryonic stem cells, primordial germ cells, and several neoplasms including serninoma, dysgerminoma, and embryonal carcinoma. Recently, immunohistochemical expression of OCT4 protein has been described in the cells within the basal layer of normal human and canine epidermis." "We have examined a series of basal cell carcinomas and adnexal tumors of related histiogenesis, in an effort to corroborate the above findings and to assess for expression of OCT4 protein in neoplasia of the infundibulo-apocrine-sebaceous unit. We analyzed OCT4 expression in...
Source: Cancer Weekly (2008-03-11)
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