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Cancer Weekly

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Bladder Cancer



Findings from A.G. Abdou and co-researchers advance knowledge in bladder cancer



March 11th, 2008

"CD10 is a cell surface zinc metalloprotease expressed in a variety of normal cell types, including lymphoid precursor cells, germinal centre B lymphocytes and some epithelial cells. The aim of this study was to assess the prognostic value of CD10 in bladder carcinoma," researchers in Egypt report.

"The expression of CD10 was immimohistochemically assessed in 49 cases of primary bladder carcinoma in comparison with 10 non-neoplastic normal bladder mucosa specimens. 27 cases (55%) were tumour CD10(+) and tumour CD 10 positivity was significantly correlated with advanced stage, larger tumor size, and shorter mean survival time. Extensive tumoral staining assessed by H...


Source: Cancer Weekly (2008-03-11)

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