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Cancer Weekly

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Breast Cancer



New breast cancer data have been reported by researchers at Herlev University



March 11th, 2008

According to a study from Herlev, Denmark, "Elevated serum levels of the protein YKL-40 are associated with a poor prognosis in patients with solid and hematologic malignancies including breast cancer. The aim of this study was to develop a valid reproducible immunohistochemical method to visualize YKL-40 expression in normal breast tissue as well as in benign and malignant breast lesions."

"The presence of YKL-40 in breast tissue was verified by in situ hybridization and protein extraction procedures. An immunohistochemical method was developed and 4 different antibodies directed against YKL-40 were tested. Ten patients with normal breast tissue and benign breast...


Source: Cancer Weekly (2008-03-11)

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