Cancer Weekly
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Breast Cancer
Research results from J. Kristek and colleagues update understanding of breast cancer
March 11th, 2008
"The aim of this paper is to determine similarities and differences between tumor cell subclones in cases of ductal invasive breast carcinoma, and which occupy primary tumor and local axillary lymph metastases. The tumor growth fraction evaluated by Ki-67 was analyzed along with the expression level of estrogen and progesterone receptors, protein p53, proto-oncogene protein bcl-2 and cathepsin D in 60 patients," scientists writing in the journal Collegium Antropologicum report. "Metastatic lymph node in axilla has a higher growth fraction of the tumor cells than the primary tumor (p=0.045), as well as the higher level of bcl-2 overexpression (p=0.014). No...
Source: Cancer Weekly (2008-03-11)
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