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Breast Cancer
Researchers from National Chung-Hsing University provide details of new studies and findings in the area of breast cancer
March 11th, 2008
"Undecylprodigiosin (UP) is a bacterial bioactive metabolite produced by Streptomyces and Serratia. In this study, we explored the anticancer effect of UP," scientists writing in the journal Toxicology and Applied Pharmacology report. "Human breast carcinoma cell lines BT-20, MCF-7, MDA-MB-231 and T47D and one nonmalignant human breast epithelial cell line, MCF-10A, were tested in this study. We found that UP exerted a potent cytotoxicity against all breast carcinoma cell lines in a dose- and time-dependent manner. In contrast, UP showed limited toxicity to MCF-10A cells, indicating UP's cytotoxic effect is selective for malignant cells. UP's cytotoxic effect was...
Source: Cancer Weekly (2008-03-11)
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