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Cancer Weekly

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Cancer Gene Therapy



Seoul National University details research in cancer gene therapy



March 11th, 2008

"The low efficiency of conventional therapies in achieving long-term survival of lung cancer patients calls for development of novel options. Aerosol gene delivery may provide the alternative for safe and effective treatment for lung cancer," researchers in Seoul, South Korea report.

"Therefore, current study was performed to elucidate the potential effects of C-terminal modulator protein (CTMP) via aerosol on lung tumorigenesis. Lentiviral vector-CTMP was delivered into K-ras null lung cancer mice through the noseonly inhalation system for 30 min. After 48 h, the potential effects of CTMP on Akt1-related signals and cell cycle regulation in the lungs were evaluated by...


Source: Cancer Weekly (2008-03-11)

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