Cancer
Researchers at Virgen of Rocio University target cancer
Published in Cancer Weekly, March 18th, 2008
"This study aimed to prospectively evaluate the potential influence of folate status on the toxicity induced by 5-fluorouracil (5-FU)-based chemotherapy in patients with gastrointestinal tumors. 105 patients with colorectal, pancreatic or gastric cancer were entered into the study. Treatment regimens consisted of bolus 5-FU/leucovorin or infusional 5-FU combined with cisplatin," scientists writing in the Journal of Chemotherapy report.
"Baseline homocysteine, vitamin B-12 and folic acid serum levels were determined in all patients. Univariate and multivariate logistic regression models were used to identify predictive factors for toxicity. Univariate analysis...
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Source: Cancer Weekly (2008-03-18)
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