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Cervical Cancer

New cervical cancer study findings recently were reported by researchers at Catholic University

Published in Cancer Weekly, March 18th, 2008

According to a study from Campobasso, Italy, "We examined the phenotype and function of CD4(+) T cells expressing the semaphorin III receptor neuropilin-1 (Nrp1) in human lymph nodes and peripheral blood. In lymph nodes, Nrp1 identified a small regulatory CD4(+) CD25(high) T-cell subpopulation (Nrp1(+) Treg) that expressed higher levels of Forkhead box P3 (Foxp3) message and protein than Nrp1(-) Treg, and various molecular markers of activated Treg, i.e."

"CD45RO, human leucocyte antigen (HLA)-DR and glucocorticoid-induced tumour necrosis factor receptor (GITR). Similarly to conventional Treg, Nrp1(+) Treg proliferated poorly in vitro, and exerted contact-dependent in...

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