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Cancer Weekly

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Cancer Gene Therapy



Researchers from German Cancer Research Center report on findings in cancer gene therapy



March 18th, 2008

Researchers detail in 'Basal caspase activity promotes migration and invasiveness in glioblastoma cells,' new data in cancer gene therapy. "Glioblastomas, the most malignant of all brain tumors, are characterized by cellular resistance to apoptosis and a highly invasive growth pattern. These factors contribute to the poor response of glioblastomas to radiochemotherapy and prevent their complete neurosurgical resection," scientists in Heidelberg, Germany report.

"However, the driving force behind the distinct motility of glioma cells is only partly understood. Here, we report that in the absence of cellular stress and proapoptotic stimuli, human glioblastoma cells...


Source: Cancer Weekly (2008-03-18)

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