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Cancer Weekly

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Cancer Vaccines Immunotherapy



Research on cancer vaccines immunotherapy detailed by scientists at Johann Wolfgang Goethe University, Department of Medicine III



March 18th, 2008

Data detailed in 'An immune escape screen reveals Cdc42 as regulator of cancer susceptibility to lymphocyte-mediated tumor suppression' have been presented. "Adoptive cellular immunotherapy inducing a graft-versus-tumor (GVT) effect is the therapeutic mainstay of allogeneic hematopoietic stem cell transplantation (ASCT) for high-risk leukemias. Autologous immunotherapies using vaccines or adoptive transfer of ex vivo-manipulated lymphocytes are clinically explored in patients with various cancer entities," scientists in Mainz, Germany report.

"Main reason for failure of ASCT and cancer immunotherapy is progression of the underlying malignancy, which is more prevalent in...


Source: Cancer Weekly (2008-03-18)

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