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Colorectal
Scientists at University of Melbourne, Department of Surgery detail research in colorectal
March 18th, 2008
Researchers detail in 'Vaccination with in vitro grown whole tumor cells induces strong immune responses and retards tumor growth in a murine model of colorectal liver metastases,' new data in colorectal. According to recent research from Heidelberg, Australia, "In vitro adaptation of a murine colorectal cell line (MoCR) rendered it less aggressive and more immunogenic than the in vivo passaged parent tumor. Vaccination of syngeneic mice with the in vitro cultured tumor cells was shown to induce immune responses and protection against tumor challenge, thus overcoming the need for antigen selection and adjuvants." "A syngeneic murine model of colorectal cancer (CRC)...
Source: Cancer Weekly (2008-03-18)
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