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Cancer Weekly

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Gene Therapy



Data on gene therapy detailed by researchers at Nihon University, College of Pharmacy



March 18th, 2008

New research, 'Treatment of Ewing's sarcoma using an antisense oligodeoxynucleotide to regulate the cell cycle,' is the subject of a report. According to recent research from Funabashi, Japan, "Ewing's sarcoma (ES) is one of the most malignant tumors of bone and soft tissue in children and young adults. ES belongs to a group of small round cell tumors (SRCTs) that also includes neuroblastoma, rhabdomyosarcoma, and malignant lymphoma."

"However, ES exhibits several specific chimeric genes (EWS-FLI1, EWS-ERG, EWS-ETV1, EWS-E1AF, and EWS-FEV) caused by chromosomal translocations that are not shared by other SRCTs. These chimeric genes regulate the expression of various...


Source: Cancer Weekly (2008-03-18)

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