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Cancer
KRAS Biomarker Analysis from Pivotal Vectibix(TM) Trial Published
March 18th, 2008
Amgen (NASDAQ: AMGN) announced that the results from a biomarker analysis of the pivotal "408" trial were published in the Journal of Clinical Oncology (JCO). The analysis showed that KRAS mutations could be used to identify patients who may not respond to treatment with Vectibix(TM) (panitumumab) monotherapy, the first fully human anti-epidermal growth factor receptor (EGFr) monoclonal antibody. These data were previously reported at the European Cancer Conference in 2007 and the Gastrointestinal Cancer Symposium in January 2008. The paper was made available early online on the JCO Web site and will be in the April 2008 print edition. These findings are the first...
Source: Cancer Weekly (2008-03-18)
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