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Cancer Weekly

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Life Sciences



Research from Duke University, Department of Pathology in life sciences provides new insights



March 18th, 2008

A new study, 'Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism,' is now available. According to recent research from the United States, "CpG oligodeoxynucleotides (ODN) stimulate the immune system and are under evaluation as treatments and vaccine adjuvants for infectious diseases, cancer, and immune system disorders. Although they have shown promising results in numerous clinical trials, the ultimate use of CpG ODN-based therapeutics may hinge on improved pharmacokinetics and reduced systemic side-effects."

"CpG ODN efficacy and potency might be enhanced greatly by packaging them...


Source: Cancer Weekly (2008-03-18)

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