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Neuroblastoma Gene Therapy
Study findings from University Children's Hospital broaden understanding of neuroblastoma gene therapy
March 18th, 2008
Fresh data on neuroblastoma are presented in the report 'Identification of DEIN, a novel gene with high expression levels in stage IVS neuroblastoma.' "Neuroblastoma at stage IVS, defined by dissemination to specific tissues and age <1 year at diagnosis, regularly follows spontaneous regression without cytotoxic treatment. To uncover the molecular characteristics of this subtype, Serial Analysis of Gene Expression (SAGE) profiles from stage IVS and fatal stage IV tumors were compared," investigators in Cologne, Germany report. "A SAGE tag (GCAACTTAAC) was detected that was overrepresented in stage IVS disease and that had no reliable match in current National Center...
Source: Cancer Weekly (2008-03-18)
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