Cancer Weekly
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Cancer Gene Therapy
Report summarizes cancer gene therapy study findings from Y. Zhang and co-researchers
March 18th, 2008
According to recent research published in the journal Gynecologic Oncology, "Previous studies have demonstrated the pivotal roles of matrix metalloproteinases (MMPs) in cervical cancer progression. Tissue inhibitor of metalloprotemases-3 (TIMP-3) can inhibit all of NIMPs, and its overexpression can retard many kinds of tumor growth." "Especially, a potent bystander effect would make it to be more advisable for treating cervical cancer whose primary growth pattern is to invade adjacent structures. These characters prompted the authors to explore its further applicability in human cervical cancer. We constructed a replication deficient adenoviral vector carrying...
Source: Cancer Weekly (2008-03-18)
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