Cancer Weekly
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Lymphoma Gene Therapy
Research from University of Buenos Aires in the area of lymphoma gene therapy published
March 25th, 2008
"The equal importance of the qualitative and quantitative characteristics of antigen presentation as well as the set of costimulatory signals provided by antigen presenting cells to T-cells in determining the outcome of T-cell responses at the time of antigen recognition is now clear. Moreover, an important function in innate mechanisms has been recently attributed to costimulatory molecules demonstrating their relevant role in different stages of immune response," scientists in Buenos Aires, Argentina report. "In this paper, we demonstrated the ability of CD40L (CD154) and CD80 costimulatory molecules expression in a T-cell lymphoma to induce both T-cell dependent and...
Source: Cancer Weekly (2008-03-25)
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