Cancer Weekly
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Cancer Gene Therapy
Reports from Northwestern University, Department of Medicine advance knowledge in cancer gene therapy
March 25th, 2008
Research findings, 'Transforming growth factor-beta 1 promotes matrix metalloproteinase-9-mediated oral cancer invasion through snail expression,' are discussed in a new report. "Oral squamous cell carcinoma (OSCC), which is the most common malignancy of the oral cavity, is often associated with local and regional invasion. Increased expression of matrix metalloproteinase-9 (MMP-9) is correlated with invasive behavior of OSCC," scientists in the United States report. "Because transforming growth factor beta1 (TGF-beta1) is up-regulated in OSCC tumors, we examined the relationship between TGF-beta1 signaling and MMP-9 in human OSCC specimens. Evaluation of human...
Source: Cancer Weekly (2008-03-25)
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