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Cancer Gene Therapy
Third Military Medical University, Department of Medical Genetics describes research in cancer gene therapy
March 25th, 2008
Scientists discuss in 'Adenovirus-mediated transfer of siRNA against peroxiredoxin I enhances the radiosensitivity of human intestinal cancer' new findings in cancer gene therapy. According to recent research published in the journal Biochemical Pharmacology, "Peroxiredoxin I (Prx-I), a key member of the peroxiredoxin family, reduces peroxides and equivalents through the thioredoxin system. Our previous work has shown that expression of Prx-I in mammalian cells increases following ionizing radiation (IR), and suppression of its expression enhances radiation-induced cell death in vitro, suggesting that inhibition of Prx-I might be an important pretreatment for cancer...
Source: Cancer Weekly (2008-03-25)
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