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Gene Therapy
Reports on gene therapy findings from New York University, Nelson Institute of Environmental Medicine provide new insights
March 25th, 2008
Scientists discuss in 'A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression' new findings in gene therapy. According to recent research from the United States, "Cyclooxygenase-2 (COX-2) is reported to be one of the early-response gene products induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). However, the relevance of COX-2 in TPA-induced cell transformation and the underlying mechanisms remains to be explored." "Initially, we verified COX-2 induction after TPA treatment in mouse embryonic fibroblasts (MEF) and mouse epidermal cells Cl 41. More importantly,...
Source: Cancer Weekly (2008-03-25)
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