Biologics

Raven biotechnologies Advances RAV18 Through Agreement With CMC ICOS Biologics

Published in Cancer Weekly, March 25th, 2008

Raven biotechnologies, inc., a privately held company focused on the discovery and development of monoclonal antibody therapeutics (MAbs) for cancer, and CMC ICOS Biologics, Inc. a leading contract manufacturing organization, announced they have entered into an agreement under which CMC ICOS will create a production cell line for Raven's next IND candidate, RAV18.

RAV18 is a humanized antibody targeting the ADAM9 protein on cells. ADAM9 is expressed on many solid tumors and is thought to contribute to disease progression and metastasis. A number of carcinoma cell lines have been shown to amplify the gene for ADAM9 and to overexpress the protein. Overexpression of ADAM9...

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Source: Cancer Weekly (2008-03-25)

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