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Acute Lymphoblastic Leukemia
Reports from University of Tehran add new data to research in acute lymphoblastic leukemia
March 25th, 2008
According to recent research published in the journal Leukemia & Lymphoma, "Wilms' tumor gene 1 (WT1) is a universal tumor-associated antigen (TAA) expressed in a variety of malignancies. High WT1 mRNA expression has been detected in the majority of acute leukemias and has been identified as a convenient marker for disease monitoring." "The aim of this study was to evaluate WT1 expression in Iranian ALL patients at diagnosis, relapse and remission. WT1 mRNA was detected in leukemic cells of ALL patients obtained at diagnosis (n=62), relapse (n=19) and remission (n=35) using a semi-quantitative RT-PCR method. In addition, peripheral blood samples from 36 healthy...
Source: Cancer Weekly (2008-03-25)
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