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Non-Hodgkin Lymphoma
Fludarabine, Mitoxantrone and Zevalin(R) Produces 96% Complete Remission Rate in First-Line Treatment of Patients with Follicular Non-Hodgkin's Lymphoma
April 1st, 2008
Cell Therapeutics, Inc. (CTI) (Nasdaq: CTIC; MTA) announced that patients with previously untreated follicular non-Hodgkin's lymphoma (NHL) treated with fludarabine and mitoxantrone, followed by administration of Zevalin(R) (Ibritumomab Tiuxetan), achieved 96 percent complete remission (CR), an estimated three-year progression-free survival (PFS) rate of 76 percent, and a 100 percent estimated three-year overall survival (OS) rate. The side effects were generally mild without any signs of cumulative toxicity, and hematological side effects were moderate. Results of the study were reported in the online edition of The Lancet (Lancet Oncology, DOI:10.1016/S1470-2045(08)70039-1). CTI acquired...
Source: Cancer Weekly (2008-04-01)
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