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Cancer Gene Therapy
University of Groningen describes research in cancer gene therapy
April 1st, 2008
Fresh data on cancer gene therapy are presented in the report 'Secretion of thymidine kinase to increase the effectivity of suicide gene therapy results in the loss of enzymatic activity.' According to recent research from Groningen, Netherlands, "Low efficiency of gene transfer is one of the major limitations of gene therapy. A solution to this problem may be transmission; by modification of the transgene, the gene product can be secreted and internalized by the surrounding cells." "Cancer gene therapy using the herpes simplex thymidine kinase (HSV-TK) suicide gene is a promising treatment, and TK has been used in clinical trials with some success. However, this kind...
Source: Cancer Weekly (2008-04-01)
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