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Adverse Drug Reactions
Studies from Medical University of Graz yield new data on adverse drug reactions
April 1st, 2008
"Hemophagocytic lymphohistiocytosis (HLH) during childhood cancer treatment is a rare adverse event posing major diagnostic and therapeutic challenges. Between 1995 and 2006, 6 children developed HLH while on conventional chemotherapy (n=4) or after allogeneic stem cell transplantation (n=2)," scientists in Graz, Austria report. "Treatment of HLH included dexamethasone and etoposide, 2 children additionally received infliximab or daclizumab. Three children survived, whereas 3 children died 2, 5, and 47 days after diagnosis of HLH. HLH is a severe adverse event of childhood cancer therapy," wrote H. Lackner and colleagues, Medical University of Graz. ...
Source: Cancer Weekly (2008-04-01)
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