Cancer Weekly
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Angiogenesis
Studies from University of Arkansas provide new data on angiogenesis
April 1st, 2008
"Tissue factor (TF), apart from its established role in hemostasis, has been implicated in promoting angiogenesis and metastasis in a wide array of tumors including prostate cancer. Expression of TF was evaluated in freshly-resected prostate specimens obtained from patients with localized (n = 9) and androgen ablated (n = 6) disease using real-time reverse transcription-polymerase chain reaction and Western blot analysis," scientists in the United States report. "TF was detected in all specimens in both stages of the disease. We further analyzed for correlations between TF expression and those of several angiogenic growth factors and their receptors. TF RNA expression...
Source: Cancer Weekly (2008-04-01)
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