Cancer Weekly
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Cancer Vaccines
Studies conducted at University of Magdeburg on cancer vaccines recently published
April 8th, 2008
"Complex perioperative immunodysfunction occurs in patients with renal cell carcinoma undergoing surgery. Here, we report on the effect of preoperative treatment with interferon-alpha 2a (IFN-alpha 2a)," scientists in Magdeburg, Germany report. "30 patients with a renal tumour received preoperative IFN-alpha 2a for 6 days beginning 1 week before nephrectomy, 30 did not. Parameters of cellular and humoral immunity were measured in venous blood at various intervals using flow cytometry and ELISA. Endpoints included effects on immune parameters, toxicity, and survival. Toxicity was grade 1 in 52%, 2 in 30%, and 3 in 4%. During IFN-alpha 2a administration, leukocytes,...
Source: Cancer Weekly (2008-04-08)
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